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OmpK36-mediated Carbapenem resistance attenuates ST258 Klebsiella pneumoniae in vivo

OmpK36-mediated Carbapenem resistance attenuates ST258 Klebsiella pneumoniae in vivo

July 12, 2025 Category: Blog

Abstract Carbapenem-resistance in Klebsiella pneumoniae (KP) sequence type ST258 is mediated by carbapenemases (e.g.KPC-2) and loss or modification of the major non-selective porins OmpK35 and OmpK36.However, the mechanism underpinning OmpK36-mediated resistance and consequences of these changes on pathogenicity remain unknown.By solving the crysta

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DETERMINATION OF ENERGY LOSSES BY SHOCK ABSORBER IN A FREIGHT CAR AT CRASH MODE

July 12, 2025 Category: Blog

Purpose.The purpose of this work is to determine the energy losses in the shock absorber of the freight car whose wheel-set moves in the derailed state on the track panel depending on the axle load and structural parameters of spring suspension.Methodology.On the basis of spring suspension construction analysis and operating principle of the fricti

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Vestibuloplasty following denture hyperplasia resection with diode laser

July 12, 2025 Category: Blog

Denture hyperplasia is a common clinical finding in patients wearing dentures.In this case report, a patient who was treated for Elbow Support denture hyperplasia presented with a post operative complication which led to inadequate vestibular depth.Inadequate vestibule is a common challenge dental surgeons encounter while considering fixed or remov

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Molecular phylogenetic analysis reveals the new genus Hemisphaericaspora of the family Debaryomycetaceae.

July 12, 2025 Category: Blog

Four strains of a novel ascomycetous yeast species were recovered from the frass of wood-boring beetles collected from Polishing Pads the Baotianman Nature Reserve and the Laojieling Nature Reserve in Henan Province, China.This species produced unconjugated and deliquescent asci with hemispheroid or helmet-shaped ascospores.Analysis of gene sequenc

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